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Dextromethorphan is largely a sigma receptor agonist and an SNRI, and dextromethorphan's effects for a dissociative hallucinogen could be attributed partially to dextrorphan (DXO), a metabolite manufactured when dextromethorphan is metabolized by the human body. Both of those dextrorphan and dextromethorphan are NMDA receptor antagonists,[32] alike

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